Peptides! they are a big deal. The most well known now are GLP1 agonists, (Ozempic etc).
A peptide is just a chain of amino acids, like a protein but shorter, our cells use these mostly for signaling.
Here’s some of the most important peptides to consider for optimal healthspan.
BPC-157: Derived from gastric juice, frequently used for healing and inflammation reduction.
TB-500: Used for repairing tissues and improving flexibility.
Epitalon: stimulates telomerase activity, which can repair and lengthen telomeres, thereby slowing cellular aging.
Thymosin Alpha-1: peptide derived from the thymus gland that acts as a potent immunomodulator, enhancing the maturation and differentiation of T-cells and increases the activity of natural killer (NK) cells, bolstering the body’s ability to fight infections and cancer.
Retatrutide: a triple action fat destroyer (FDA approval expected this year). There’s evidence pointing to the healthspan benefits of the GLP1 peptides go beyond just the weight loss.
MOTS-c -is a mitochondria-derived peptide that promotes longevity by improving metabolic flexibility, enhancing insulin sensitivity, and activating the AMPK signaling pathway. It mimics the effects of exercise and fasting, often dubbed “exercise in a vial,” aiding in fat loss and mitochondrial health.
GHK-Cu: a naturally occurring copper peptide that declines with age, it is a potent tissue-protective, anti-inflammatory, and anti-aging agent. It accelerates wound healing, stimulates collagen synthesis, improves skin elasticity, and promotes hair growth. There is robust research on this peptide and we have just added GHK-Cu to our site. GHK-Cu is on sale!
α-Klotho: ok, officially this is a protein, but it has remarkable research and should not be overlooked by anyone serious about their long term health (especially kidney health). Klotho functions as a longevity hormone, promoting anti-inflammatory, anti-oxidative, and anti-fibrotic effects, while regulating kidney health. Moreover, the protective effect of klotho extends to other pathological conditions, including cardiovascular diseases, Alzheimer’s disease, cancer, inflammatory bowel disease, and liver disease. We are expecting a new batch soon, so have made it available for pre-order.
Safety? The FDA has just removed a bunch of popular peptides from their naughty list. And an oral version of Ozempic has just been ok’d by FDA.
Stacking? unclear on how they interact– but your blood is always a chaos of thousands of chemicals bumping into each other, and there appears to be many successful combinations like the “Wolverine stack” (BPC-157 & TB-500).